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. 2021 Dec 14;11:773063. doi: 10.3389/fonc.2021.773063

Figure 5.

Figure 5

CD248+ CAF infiltration was suggestive of a poor prognosis in RCC patients and immunosuppression. (A) Kaplan–Meier analysis of the OS associated with high and low CD248+ CAF infiltration. (B) Clinicopathological correlation of CD248+ CAF infiltration in RCC. (C) Correlation analysis between the CAF infiltration score and TME scores. (D) Box plot of the comparison of cells in the TME based on high and low CD248+ CAF infiltration groups. (E) Heatmap of TME cells shown after grouping by CD248+ CAFs. (F) Box plot of the comparison of inhibitory immune molecules based on high and low CD248+ CAF infiltration groups. p < 0.05 was considered statistically significant. **p < 0.01; ***p < 0.001.