Skip to main content
. 2021 Dec 14;8:797195. doi: 10.3389/fmed.2021.797195

Table 1.

YTHDF2 rs3738067 A>G polymorphism and neuroblastoma susceptibility.

Genotype Cases (%) (N = 896) Controls (%) (N = 1,733) P a Crude OR (95% CI) P Adjusted OR (95% CI)b P b
rs3738067 (HWE=0.359)
AA 535 (59.71) 944 (54.47) 1.00 1.00
AG 292 (32.59) 680 (39.24) 0.76 (0.64–0.90) 0.002 0.76 (0.64–0.90) 0.002
GG 69 (7.70) 109 (6.29) 1.12 (0.81–1.54) 0.498 1.12 (0.82–1.55) 0.478
Additive 0.134 0.91 (0.79–1.03) 0.134 0.91 (0.80–1.03) 0.143
Dominant 361 (40.29) 789 (45.53) 0.010 0.81 (0.69–0.95) 0.010 0.81 (0.69–0.95) 0.011
Recessive 827 (92.30) 1,624 (93.71) 0.172 1.24 (0.91–1.70) 0.173 1.25 (0.91–1.71) 0.165

OR, odds ratio; CI, confidence interval; HWE, Hardy-Weinberg equilibrium.

Values were in bold if the P-values <0.05 or the 95% CIs excluded 1.

a

χ2 test for genotype distributions between neuroblastoma cases and cancer-free controls.

b

Adjusted for age and gender.