Table 1.
Genotype | Cases (%) (N = 896) | Controls (%) (N = 1,733) | P a | Crude OR (95% CI) | P | Adjusted OR (95% CI)b | P b |
---|---|---|---|---|---|---|---|
rs3738067 (HWE=0.359) | |||||||
AA | 535 (59.71) | 944 (54.47) | 1.00 | 1.00 | |||
AG | 292 (32.59) | 680 (39.24) | 0.76 (0.64–0.90) | 0.002 | 0.76 (0.64–0.90) | 0.002 | |
GG | 69 (7.70) | 109 (6.29) | 1.12 (0.81–1.54) | 0.498 | 1.12 (0.82–1.55) | 0.478 | |
Additive | 0.134 | 0.91 (0.79–1.03) | 0.134 | 0.91 (0.80–1.03) | 0.143 | ||
Dominant | 361 (40.29) | 789 (45.53) | 0.010 | 0.81 (0.69–0.95) | 0.010 | 0.81 (0.69–0.95) | 0.011 |
Recessive | 827 (92.30) | 1,624 (93.71) | 0.172 | 1.24 (0.91–1.70) | 0.173 | 1.25 (0.91–1.71) | 0.165 |
OR, odds ratio; CI, confidence interval; HWE, Hardy-Weinberg equilibrium.
Values were in bold if the P-values <0.05 or the 95% CIs excluded 1.
χ2 test for genotype distributions between neuroblastoma cases and cancer-free controls.
Adjusted for age and gender.