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. 2021 Dec 14;11:786929. doi: 10.3389/fcimb.2021.786929

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Copyright © 2021 Rodriguez-Urretavizcaya, Pascual, Pastells, Martin-Gomez, Vilaplana and Marco

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Growth curves and phenazines kinetics production of two P. aeruginosa isolates grown for 48 h. The green line (OD 600) gives information about the bacterial growth. The blue and the orange lines indicate IRequiv. of pyocyanin (PYO) and 1-hydroxyphenazine (1-OHphz) production, respectively. Results obtained (A) from an isolate (PAAI20) of a patient undergoing an acute P. aeruginosa infection and (B) from an isolate (PACI18) of a patient suffering chronic infection. The data shown are the average and standard deviation of IRequiv. of PYO and 1-OHphz determinations performed with the corresponding ELISAs on the same day using three well replicates.