Table 2.
Comparison of frequencies of events between the 2 periods (incidence >2%).
| SOCm | Number of ADRs (%) “pre-COVID” |
Number of ADRs (%) “COVID” |
|---|---|---|
| Cutaneous disorders* | 885 (32.5%) | 22(6.3%) |
| Neurological disorders* | 251 (9.2%) | 7 (2%) |
| Haematological disorders* | 236 (8.7%) | 9 (2.6%) |
| Eye disorders* | 211 (7.7%) | 7 (2.0%) |
| Gastrointestinal disorders | 183 (6.7%) | 33 (9.4%) |
| General disorders* | 136 (5.0%) | 7 (2.0%) |
| Cardiac disorders* | 128 (4.7%) | 199 (56.7%) |
| Hepatobiliary disorders* | 121 (4.4%) | 37 (10.5%) |
| Musculoskeletal disorders* | 101 (3.7%) | 1 (0.3%) |
| Hearing disorders* | 74 (2.7%) | 1 (0.3%) |
| Infections | 71 (2.6%) | 4 (1.1%) |
| Psychiatric disorders | 65 (2.4%) | 3 (0.9%) |
| Metabolic disorders* | 30 (1.1%) | 10 (2.8%) |
| Others | 235 (8.6%) | 11 (3.1%) |
ADR: adverse drug reactions; COVID: coronavirus disease; SOC: system organ class.
*
P < 0.05.