Table 1.
Demographic data of subjects.
| Variables | Control | Low sCD163 group | High sCD163 group | P-value Control | P-value Low |
|---|---|---|---|---|---|
| (n =78) | (n = 150) | (n = 150) | vs. patients | vs. High | |
| Age, Mean (SD) | 62.86 (10.89) | 64.83 (9.20) | 65.16 (9.34) | 0.082 | 0.756a |
| Male, No. (%) | 48 (61.54) | 95 (63.33) | 75 (50.00) | 0.520 | 0.027b |
| BMI, Median (IQR) | 23.85 (22.28, 25.33) | 24.68 (23.14, 25.76) | 24.19 (22.96, 25.37) | 0.029 | 0.086c |
| Smoking history, No. (%) | 7 (8.97) | 11 (7.33) | 16 (10.67) | 0.437 | 0.420b |
| Antiplatelet drug use, No. (%) | 9 (11.54) | 21 (14.00) | 19 (12.67) | 0.850 | 0.865b |
| Antithrombotic drug use, No. (%) | 4 (5.13) | 13 (8.67) | 6 (4.00) | 1.000 | 0.153b |
| Family history of stroke, No. (%) | 3 (3.85) | 9 (6.00) | 9 (6.00) | 0.587 | 1.000b |
| Comorbidities | |||||
| Hypertension, No. (%) | 21 (26.92) | 52 (34.67) | 51 (34.00) | 0.226 | 1.000b |
| Diabetes Mellitus, No. (%) | 13 (16.67) | 26 (17.33) | 23 (15.33) | 1.000 | 0.755b |
| Hypercholesteremia, No. (%) | 6 (7.69) | 9 (6.00) | 19 (12.67) | 0.825 | 0.072b |
| Arial fibrillation, No. (%) | 7 (8.97) | 13 (8.67) | 6 (4.00) | 0.451 | 0.153b |
| DWI hyperintensity volume, ml (SD) | NA | 24.56 (8.86) | 32.36 (7.53) | NA | 0.000 a |
| NIHSS at baseline, Median (IQR) | NA | 8 (3, 13) | 15 (11.75, 19) | NA | 0.000c |
| NIHSS at follow-up, Median (IQR) | NA | 4 (1, 9) | 6 (3, 7) | NA | 0.595c |
| mRS at follow-up, Median (IQR) | |||||
| Stroke etiology | |||||
| Atherothrombotic, No. (%) | NA | 122 (81.33) | 131 (87.33) | NA | 0.204b |
| Cardioembolic, No. (%) | NA | 13 (8.67) | 6 (4.00) | NA | 0.153b |
| Lacunar, No. (%) | NA | 13 (8.67) | 4 (2.67) | NA | 0.043b |
| Unknown, No. (%) | NA | 2 (1.33) | 9 (6.00) | NA | 0.061b |
| Complication | |||||
| Hemorrhagic transformation, No. (%) | NA | 3 (2.00) | 7 (4.67) | NA | 0.335b |
| Recurrent AIS, No. (%) | NA | 4 (2.67) | 1 (0.67) | NA | 0.371b |
| rtPA treatment, No. (%) | NA | 13 (8.67) | 16 (10.67) | NA | 0.697b |
| mRS scores, Median (IQR) | NA | 2 (0, 4) | 3 (2, 3) | NA | 0.641c |
IQR, Inter-Quartile Range; BMI, Body Mass Index; TICS, Telephone Interview of Cognitive Status 40; NIHSS, National Institutes of Health Stroke Scale; NA, not applicable.
a
Unpaired t-test;
b
Pearson χ2-test;
c
Mann-Whitney U-test. Bold values represents statistically significant.