FIGURE 5.

SNARE-binding core domain of cpx1 is responsible for increased probability of large fusion pore formation. (A) Bar graph displays the distribution of the percent of vesicles showing large fusion pore forming events among docked vesicles with no cpx1 (red), with WT cpx1, and with N-terminal truncation mutants of cpx1. The data is shown as means ± SD. **p ˂ 0.01 by Students’ t-test; n = 3 independent experiments. (B) Bar graph displays the percent of vesicles showing the large fusion pore events among docked vesicles without cpx1, with WT cpx1, and with the C-terminal truncation mutants of cpx1. The data is shown as means ± SD. **p ˂ 0.01 by Students’ t-test; n = 3 independent experiments.