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. 2021 Dec 14;12:762587. doi: 10.3389/fgene.2021.762587

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Copyright © 2021 Hu, Shu, Ma, Chen, Wang, Wang, Lin and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The family tree of the proband. * signified that the patient was taking the lipid-lowering drug (atorvastatin 20 mg); → represented the proband. In the current study, the background of the FH patients’ (I-1, II-1) picture was blackened. The disease-causing variants in LDLR were bolded.