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. 2021 Dec 14;11:761169. doi: 10.3389/fonc.2021.761169

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Copyright © 2021 Zhylka, Sollmann, Kofler, Radwan, De Luca, Gempt, Wiestler, Menze, Krieg, Zimmer, Kirschke, Sunaert, Leemans and Pluim

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of the radial extent of the corticospinal tract (CST) branches. This figure shows the radial extents (with median values as vertical dashed lines) for the CST reconstructions derived from diffusion tensor imaging (DTI)-based tractography, constrained spherical deconvolution (CSD)-based tractography, and multi-level fiber tracking (MLFT). Columns for the tumor-affected hemispheres are displayed in orange, columns for the unaffected hemispheres are depicted in blue. The affected hemispheres show higher radial extent in case of each of the used tractography algorithms. The p-values are derived from comparisons between hemispheres per tractography algorithm (Wilcoxon signed-rank paired tests with significance level α=0.05).