Table 3.
Commercially available PoCT kits for SARS-CoV-2 detection with nucleic acid target analytes.
| Detection Method | Target Analyte | Sensitivity (%) | Specificity (%) | Detection Time | Reference |
|---|---|---|---|---|---|
| RCA with magnetic nanoparticles | Synthetic complementary DNA (RdRp) | N/A | N/A | <2 h | (52) |
| CRISPR-based LAMP with lateral flow assay | RNA (E, N genes) | 95 | 100 | <1 h | (53) |
| Real-time qRT-PCR | RNA (RdRp, E, N genes) | 100 | 100 | >4 h | (40) |
| Reverse transcription-LAMP | RNA | N/A | N/A | <1 h | (49) |
| LAMP with colorimetric readout | RNA | N/A | N/A | <1 h | (54) |
| Digital PCR | RNA | N/A | N/A | <1 h | (55) |
| Reverse transcription-LAMP | RNA (ORF1ab, S genes) | 100 | 100 | <1 h | (56) |
| Reverse transcription-LAMP | RNA | N/A | N/A | <1 h | (57) |
N/A, not available.