Table 2.
Baseline vs. 1 year cardiac magnetic resonance measurements in patient groups
| Variable | At risk (baseline) | At risk (1 year) | P value | HFpEF (Baseline) | HFpEF (1 year) | P value | HFrEF (Baseline) | HFrEF (1 year) | P value |
|---|---|---|---|---|---|---|---|---|---|
| LVEF, % | 64 (59, 70) | 65 (60, 70) | 0.08 | 61 (55, 65) | 62 (55, 67) | 0.43 | 42 (35, 45) | 46 (39, 51) | <0.001 |
| LVEDVi, mL/m2 | 65 (58, 78) | 68 (56, 77) | 0.27 | 66 (58, 77) | 67 (56, 77) | 0.37 | 98 (79, 116) | 87 (72, 111) | 0.07 |
| LVESVi, mL/m2 | 24 (18, 31) | 23 (18, 29) | 0.06 | 26 (20, 32) | 25 (19, 32) | 0.11 | 55 (44, 72) | 45 (38, 63) | <0.001 |
| LV massi, g/m2 | 54 (45, 69) | 56 (48, 64) | 0.32 | 56 (48, 67) | 58 (50, 70) | 0.05 | 73 (61, 82) | 70 (57, 82) | 0.09 |
| LV mass/LVEDV | 0.81 (0.72, 0.91) | 0.83 (0.75, 0.90) | 0.55 | 0.85 (0.71, 0.96) | 0.85 (0.75, 0.99) | 0.13 | 0.74 (0.64, 0.88) | 0.76 (0.66, 0.87) | 0.37 |
| RVEF, % | 60 (55, 66) | 60 (54, 66) | 0.76 | 57 (51, 62) | 57 (50, 65) | 0.29 | 52 (45, 57) | 53 (45, 57) | 0.72 |
| RVEDVi, mL/m2 | 69 (55, 76) | 62 (53, 71) | <0.001 | 64 (53, 77) | 62 (50, 75) | 0.009 | 73 (64, 92) | 72 (54, 84) | 0.005 |
| RVESVi, mL/m2 | 26 (20, 33) | 25 (19, 31) | 0.002 | 28 (22, 35) | 26 (20, 35) | 0.01 | 33 (27, 43) | 33 (25, 40) | 0.12 |
| LAVi, mL/m2 | 37 (29, 48) | 40 (28, 48) | 0.99 | 51 (36, 71) | 51 (38, 66) | 0.35 | 53 (43, 63) | 52 (49, 62) | 0.44 |
| GLS, % | −18.9 ± 3.6 | −19.1 ± 3.1 | 0.34 | −18.0 ± 3.3 | −17.2 ± 4.0 | 0.03 | −11.9 ± 2.8 | −12.8 ± 3.9 | 0.01 |
| GCS, % | −19.2 ± 3.2 | −19.1 ± 3.6 | 0.66 | −18.5 ± 3.6 | −18.0 ± 4.0 | 0.18 | −11.2 ± 3.0 | −11.9 ± 3.2 | 0.03 |
| Scar prevalence, %* | 20 (24%) | 20 (24%) | 1.0 | 16 (37%) | 21 (41%) | 0.18 | 28 (51%) | 36 (73%) | 0.008 |
| Scar mass, g* | 0 (0, 0) | 0 (0, 0) | 0.65 | 0 (0, 5.8) | 0 (0, 6.1) | 0.44 | 7.0 (0, 24.2) | 8.8 (0, 25) | 0.002 |
| Scar %LV* | 0 (0, 0) | 0 (0, 0) | 0.36 | 0 (0, 5.3) | 0 (0, 5.6) | 0.89 | 6 (0, 16.2) | 6.8 (0, 16) | 0.01 |
Abbreviations: GCS, global circumferential strain; GLS, global longitudinal strain; HFpEF, heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction; LAVi, left atrial volume index; LV massi, left ventricular mass index; LVEDVi, left ventricular end‐diastolic volume index; LVEF, left ventricular ejection fraction; LVESVi, left ventricular end‐systolic volume index; RVEDVi, right ventricular end‐diastolic volume index; RVEF, right ventricular ejection fraction; RVESVi, right ventricular end‐systolic volume index.
Continuous variables expressed as mean ± SD or median (25–75th percentile), as appropriate. P values for comparison between baseline and 1 year measurement.
183/262 patients underwent late gadolinium enhancement imaging at both baseline and 1 year.