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. 2021 Dec 14;9:726931. doi: 10.3389/fcell.2021.726931

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Copyright © 2021 Dong, Feng, Yang, Hu, Jia, Yang, Zhao and Zhao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PCK2 is increased in Kupffer cells after acute LPS administration in mice. (A) Immunohistochemical staining and quantification of F4/80 and CD68 in the liver (magnification, x400). (B) The expression levels of inflammatory cytokines were determined by real-time PCR. (C) The levels of inflammatory cytokines in plasma were determined by cytometric bead array (CBA). (D) Co-immunofluorescence staining of PCK2 and CD68. Values are mean ± SEM, n = 6. **p < 0.01 versus control group.