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. 2021 Dec 14;9:726931. doi: 10.3389/fcell.2021.726931

FIGURE 5.

FIGURE 5

PCK2 promotes inflammation via regulating NF-κB activation. (A) The total protein expression of IKKα, p-p65, and p65 was determined by Western blot after 3MP treatment. (B) The total protein expression of IKKα, p-p65, and p65 was determined by Western blot after PCK2 knockdown. (C) The total protein expression of p-p65 and p65 were determined by Western blot after PCK2 overexpression (PCK2 OE). (D) Representative fluorescence images of p65 nuclear translocation in Kupffer cells after PCK2 overexpression (PCK2 OE). (scale bar: 10μm). Values are mean ± SEM. *p < 0.05, **p < 0.01.