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. 2021 Dec 14;8:731106. doi: 10.3389/fmed.2021.731106

Table 1.

Demographics and clinical characteristics of patients.

Variable Hemorrhage Group (n = 18) No-hemorrhage Group (n = 42) P -value
Age, years 48.5 ± 11.7 48.0 ± 14.6 0.899
Gender 0.231
Male 12 (66.7%) 34 (81.0%)
Female 6 (33.3%) 8 (19.0%)
Comorbidities
Hypertension 9 (50.0%) 13 (40.1%) 0.161
Diabetes 2 (11.1%) 2 (4.8%) 0.576
Preexisting Cardiac Disorder 8(44.4%) 12 (28.6%) 0.232
Chronic Obstructive Pulmonary Diseases 3 (16.7%) 1 (2.4%) 0.077
Chronic Kidney Diseases 2 (11.1%) 0 (0) 0.086
Cancer 1 (5.6%) 1 (2.4) 0.514
Anti-platelet or anticoagulant history 7 (38.9%) 15 (35.7%) 0.859
Cause of ECMO Therapy
Cardiogenic Shock 7 (38.9%) 25 (59.5%) 0.142
Respiratory failure 4(22.2%) 2 (4.8%) 0.060
Infectious shock 3 (16.7%) 1(2.4%) 0.077
Traumatic shock 2 (11.1%) 5 (11.9%) 1.000
Electrical injury 0 (0) 2 (4.8%) 1.000
Intoxication 0 (0%) 1 (2.4%) 1.000
Aortic dissection 1 (5.6%) 3 (7.1%) 1.000
Others 1 (5.6%) 3 (7.1%) 1.000
APACHE II 26.2 ± 7.1 24.9 ± 10.2 0.621
Body temperature pre-ECMO, °C 36.8 37.1 0.598
Time from onset to ECMO initiation, h 9.0 (5.0–19.25) 3.0 (1.0–6.5) 0.002*
Duration of ECMO support, h 141.3 (72.0–288.0) 27.3 (8.8–87.5) 0.001*
Mode 0.008*
V-V ECMO 5 (27.8%) 1 (2.4%)
V-A ECMO 13 (72.2%) 41 (97.6%)
ECMO combined with CRRT 5 (27.7%) 6 (14.3%) 0.216
Outcome 0.389
Mortality 14 (77.8%) 28 (66.7%)
Discharge 4 (22.2%) 14 (33.3%)

Data are mean ± standard, median (IQR), n (%). P-values were calculated by Mann-Whitney U-test, χ2 test, or Fisher's exact test, as appropriate. COPD, Chronic Obstructive Pulmonary Disease; CKD, Chronic Kidney Disease; APACHE, Acute Physiological and Chronic Health Evaluation; CRRT, Continuous Renal Replacement Therapy.

*

P-value < 0.05.