TABLE 2.

Significance of several microRNAs (miRs) in vascular aging process (based on a systematic review by Navickas et al., 2016).

Process	Type of microRNAs
Endothelial function and angiogenesis	miR-1, miR-133
Vascular smooth muscle cell differentiation	miR-133, miR-145
Communication between vascular smooth muscle and endothelial cell to stabilize plaques	miR-145
Apoptosis	miR-1, miR-133, miR-499
Cardiac myocyte differentiation	miR-1, miR-133, miR-145, miR-208, miR-499
Repression of cardiac hypertrophy	miR-133