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LINC01572 increases glycolysis and activates PI3K/AKT signaling by regulating the PFKFB4 expression. (A,B) ATP production, (C,D) glucose consumption, and (E,F) lactate production following transfection of indicated constructs. (G,H) Effect of PFKFB4 overexpression or silencing on PI3K/AKT signaling, following LINC01572 silencing or overexpression, respectively. All data are shown as mean ± standard deviation (n = 3). ** p < 0.01.
