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. 2021 Dec 14;9:783088. doi: 10.3389/fcell.2021.783088

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Copyright © 2021 Lai, Quan, Hao, Liu, Wang, Dai, Dai, He and Tang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PFKFB4 reverses LINC01572 provoked inhibition of proliferation, invasion, and migration in HCC cells. (A) RT-qPCR was used to detect the PFKFB4 level. (B,C) cck-8 and colony formation assays assessing the proliferation ability following LINC01572 silencing in the presence or absence of PFKFB4 overexpression. (D,E) Effect of LINC01572 silencing on HCC cell migration, invasion, and EMT marker expression in the presence or absence of PFKFB4 overexpression. All data are shown as mean ± standard deviation (n = 3). ^** p < 0.01.