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. 2021 Sep 14;8(6):4944–4954. doi: 10.1002/ehf2.13534

Table 2.

Univariable and multivariable models of the association between clinical or haemodynamic profiles and estimated glomerular filtration rate < 60 mL/min/1.73 m2

Crude associations Adjusted associations
OR 95% CI P‐value OR 95% CI P‐value
Haemodynamic variables
CVP per 1 mmHg 1.07 1.02–1.12 0.004 1.05 1.00–1.11 0.065
CVP > 10 mmHg 2.79 1.49–5.22 0.001 2.21 1.05–4.66 0.036
mPAP per mmHg 1.03 1.00–1.06 0.072 1.00 0.97–1.04 0.881
mPAP > 25 mmHg 1.31 0.72–2.40 0.376 0.90 0.43–1.89 0.780
PCWP per mmHg 1.02 0.99–1.06 0.220 0.99 0.95–1.04 0.997
PCWP > 22 mmHg 1.34 0.72–2.50 0.356 0.91 0.43–1.90 0.797
CI per 1 L/min/m2 0.67 0.38–1.19 0.171 1.18 0.67–2.08 0.560
CI < 2.1 L/min/m2 1.40 0.75–2.60 0.287 1.11 0.54–2.30 0.769
PVR per Wood unit 1.15 0.93–1.41 0.188 1.01 0.81–1.27 0.906
CVP/PCWP 2.51 1.02–6.20 0.045 2.24 0.81–6.18 0.118
PAPi 0.96 0.90–1.03 0.278 0.99 0.91–1.07 0.772
RVSWI 1.00 0.92–1.07 0.936 0.97 0.88–1.06 0.483
Clinical and functional variables
SBP per mmHg 0.99 0.97–1.01 0.203 0.99 0.96–1.01 0.258
SBP < 90 mmHg 1.80 0.89–3.60 0.099 1.68 0.74–3.79 0.214
DBP per mmHg 0.99 0.97–1.02 0.610 1.00 0.97–1.03 0.918
NYHA class per 1 unit 1.35 0.83–2.18 0.224 1.09 0.62–1.92 0.768
VO2 max per mL/kg/min 0.93 0.84–1.02 0.140 0.99 0.88–1.12 0.905

95% CI, 95% confidence interval; CI, cardiac index; CVP, central venous pressure; DBP, diastolic blood pressure; HR, heart rate; mPAP, mean pulmonary arterial pressure; NYHA, New York Heart Association; OR, odds ratio; PAPi, pulmonary artery pulsatility index; PCWP, pulmonary capillary wedge pressure; PVR, pulmonary vascular resistance; RVSWI, right ventricular stroke work index; SBP, systolic blood pressure, VO2 max, maximum oxygen consumption rate.

Model adjusted for age, BNP Z‐score, and history of hypertension.