Table 5.
Prevalence of fluctuations and dyskinesia according to gender at the start of treatment with safinamide and during the follow-up.
| Motor complications | Gender | Baseline | 4 months | 8 months | 12 months |
|---|---|---|---|---|---|
| Any fluctuations | Female | 93.6% | 78.2% | 74.6% | 71.8% |
| Male | 91.6% | 71.3% | 69.2% | 66.3% | |
| Wearing-off | Female | 76.5% | 58.5% | 56.7% | 56.0% |
| Male | 73.5% | 52.8% | 52.3% | 51.7% | |
| Dyskinesia | Female | 48.8% | 44.6% | 39.9% | 35.1% |
| Male | 33.2% | 28.3% | 26.6% | 23.3% | |
| Early morning fluctuations | Female | 25.7% | 15.1% | 16.8% | 14.4% |
| Male | 21.5% | 13.0% | 13.5% | 13.1% | |
| Unpredictable fluctuations | Female | 17.5% | 11.0% | 11.1% | 11.0% |
| Male | 16.2% | 11.2% | 11.2% | 9.2% | |
| Delayed ON | Female | 11.9% | 9.8% | 8.5% | 8.1% |
| Male | 11.0% | 7.2% | 7.8% | 8.6% |
Percentages (%) were computed by column.