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. 2021 Dec 14;12:756304. doi: 10.3389/fneur.2021.756304

Table 5.

Prevalence of fluctuations and dyskinesia according to gender at the start of treatment with safinamide and during the follow-up.

Motor complications Gender Baseline 4 months 8 months 12 months
Any fluctuations Female 93.6% 78.2% 74.6% 71.8%
Male 91.6% 71.3% 69.2% 66.3%
Wearing-off Female 76.5% 58.5% 56.7% 56.0%
Male 73.5% 52.8% 52.3% 51.7%
Dyskinesia Female 48.8% 44.6% 39.9% 35.1%
Male 33.2% 28.3% 26.6% 23.3%
Early morning fluctuations Female 25.7% 15.1% 16.8% 14.4%
Male 21.5% 13.0% 13.5% 13.1%
Unpredictable fluctuations Female 17.5% 11.0% 11.1% 11.0%
Male 16.2% 11.2% 11.2% 9.2%
Delayed ON Female 11.9% 9.8% 8.5% 8.1%
Male 11.0% 7.2% 7.8% 8.6%

Percentages (%) were computed by column.