Skip to main content
. Author manuscript; available in PMC: 2021 Dec 28.
Published in final edited form as: Cell Rep. 2020 Jun 30;31(13):107781. doi: 10.1016/j.celrep.2020.107781

Figure 6. Proposed Model for Function of CARMIL1 in IL-1 Signaling.

Figure 6.

In spreading cells, FAs are formed under the extracellular matrix. In the FA complexes, the leucine-rich repeat region of CARMIL1 regulates the recruitment of effector molecules IL-1R1 and IRAK to facilitate the regulatory processes involved in IL-1-mediated ERK to MMP pathway.