Table 1.

Multidrug resistant bacteria observed in the community, classified according to CDC threat level.

MDR Phenotype	Epidemiologic setting of community-onset infections
Urgent Threats
CR-AB	Extremely rare
Candida auris	Extremely rare
Clostridioides difficile	Prior antibiotic exposure; nursing homes
CRE	Rare at present; emerging in India and China
Drug-resistant Neisseria gonorrhoeae	Exclusively community-onset
Serious threats
Drug-resistant Campylobacter	Exclusively community-onset
Drug-resistant Candida	Rare at present; prior azole exposure typical
ESBL + Enterobacterales	Endemic in most parts of the world
VRE	Rare except in nursing home residents
CR-PA	Extremely rare, except in those with suppurative lung disease and extensive antibiotic use
Drug-resistant nontyphoidal Salmonella	Exclusively community-onset
Drug-resistant Salmonella serotype Typhi	Exclusively community-onset
Drug-resistant Shigella	Exclusively community-onset
MRSA	Household colonization; farm animal exposure
Drug-resistant Streptococcus pneumononiae	Almost exclusively community-onset
Drug-resistant tuberculosis	Predominantly community-onset