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. 2021 Dec 14;11:766427. doi: 10.3389/fcimb.2021.766427

Table 4.

Ordinal logistic regression analysis of the H. pylori infection and the severity of TN types.

C14 test The classification of TN types, n (%) Model 1 Model 2 Model 3
Negative TI-RADS ≤ 2 TI-RADS3 TI-RADS≥4 OR (95% CI) OR (95% CI) OR (95% CI)
H. pylori (−) 18,139 (59.7%) 1,603 (56.2%) 5,556 (58.8%) 416 (57.1%) 1.00 (reference) 1.00 (reference) 1.00 (reference)
H. pylori (+) 12,236 (40.3%) 1,251 (43.8%) 3,897 (41.2%) 313 (42.9%) 1.06 (1.02–1.11) 1.01 (0.96–1.06) 1.01 (0.96–1.05)
P value 0.005* 0.695 0.848

Model 1: unadjusted; Model 2: adjusted for sex, age, BMI, systolic, diastolic; Model 3: Model 2 + adjusted for TCH, TG, LDL, and HDL.

TN, thyroid nodule; C14 test, carbon-14 urea breath test; CI, confidence interval; BMI, body mass index; SP, systolic pressure; DP, diastolic pressure; TCH, total cholesterol; TG, triglyceride; LDL, low-density lipoprotein; HDL, high-density lipoprotein.

*P value is considered statistically significant.