Agertoft 1997.

Methods	Setting: Denmark, paediatric outpatient clinic Randomisation: yes, computerised scheme prepared in balanced blocks Allocation concealment: unclear Design: crossover, 2 week washout Intervention period: 2 weeks Masking: double blind Excluded: none Withdrawals: stated Baseline characteristics: comparable Jadad score=4
Participants	48 children: 27M 21F Age range: 6 to 12 years Inclusion criteria: Clinical diagnosis of mild asthma requiring treatment with beta2 agonists only Exclusion criteria: Use of oral or inhaled steroids
Interventions	BUD: 1. 200 mcg/d 2. 400 mcg/d Placebo Delivery device: Turbohaler DPI
Outcomes	Knemometry 24 urinary free cortisol excretion
Notes	This study also included treatment arms with fluticasone 200 mcg/d and 400 mcg/d: results not considered in this review.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear