Fuller 1991.
Methods | Setting: UK, hospital outpatient clinic Randomisation: yes, method not stated Allocation concealment: unclear Design: crossover, 3 week washout Intervention period: 3 weeks Masking: double blind Excluded: not stated Withdrawals: stated Baseline characteristics: comparable Jadad score=3 | |
Participants | 10 subjects: 6M 4F Age range: 18‐45 years Inclusion criteria: Mild asthma requiring only irregular therapy with inhaled beta2 agonists Exclusion criteria: Not stated | |
Interventions | BUD: 600 mcg 2xdaily (1200 mcg/d) Placebo: twice daily Delivery device: MDI+spacer |
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Outcomes | FEV1 Morning PEFR Evening PEFR Bradykinin BHR (PD 35 Sgaw) Histamine BHR (PD 35 Sgaw) | |
Notes | No reply from author to clarify details of randomisation method. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |