Table 3.
Follow up changes in Anthropometric Characteristics, Biochemical Parameters and Serum Adipo-cytokines in individuals with obesity (n=30) undergoing different bariatric procedures.
| GASTRECTOMY |
GASTRIC BYPASS |
|||||
|---|---|---|---|---|---|---|
| BASELINE (n=18) | POST-OP (n=18) | FOLLOW UP (n=9) | BASELINE (n=12) | POST-OP (n=12) | FOLLOW UP (n=9) | |
| Anthropometric Characteristics: | ||||||
| Body Weight (Kg) | 118.2 ± 6.23 | – | 85.73 ± 5.71*** | 123.1 ± 8.21 | – | 90.69 ± 5.77** |
| BMI (Kg/m2) | 45.99 ± 1.45 | – | 33.21 ± 1.18*** | 46.29 ± 2.05 | – | 34.48 ± 1.38*** |
| Glucose Homeostasis: | ||||||
| Fasting Serum Glucose (mg/dL) | 99.26 ± 5.10 | – | 92.98 ± 5.48 | 101.8 ± 4.56 | – | 92.33 ± 4.28 |
| Fasting Serum Insulin (μU/L) | 16.47 ± 3.25 | – | 5.99 ± 0.78** | 25.98 ± 3.18 | – | 10.37 ± 1.85*** |
| HbA1c | 5.75 ± 0.13 | – | 5.58 ± 0.21 | 6.13 ± 0.24 | – | 5.57 ± 0.23 |
| HOMA-IR | 3.61 ± 0.72 | – | 1.36 ± 0.2** | 6.45 ± 0.81 | – | 2.33 ± 0.42*** |
| HOMA-B | 264.2 ± 75.93 | – | 101.8 ± 15.58 | 284.7 ± 52.43 | – | 165.8 ± 46.88 |
| QUICKI | 0.33 ± 0.01 | – | 0.37 ± 0.01** | 0.30 ± 0.007 | – | 0.34 ± 0.01** |
| Serum Inflammatory Cytokines: | ||||||
| CRP (μg/mL) | 29.66 ± 24.03 | 50.02 ± 31.89 | 10.48 ± 5.47 | 37.21 ± 26.56 | 61.58 ± 31.77 | 6.77 ± 2.40*** |
| TNF-α (pg/mL) | 15.62 ± 2.5 | 12.78 ± 1.87 | 37.80 ± 8.77** | 43.32 ± 9.48 | 32.88 ± 7.35 | 29.87 ± 4.97 |
| IL8 (pg/mL) | 74.41 ± 33.74 | 68.04 ± 31.06 | 67.86 ± 19.64 | 214.2 ± 114.9 | 110.7 ± 47.24 | 119.1 ± 42.58 |
| MCP1 (ng/mL) | 0.94 ± 0.08 | 0.82 ± 61.5 | 0.80 ± 0.06 | 1.04 ± 0.11 | 1.01 ± 0.15 | 0.70 ± 0.08* |
| IL6 (pg/mL) | 17.82 ± 4.06 | 43.41 ± 19.75 | 93.98 ± 80.64 | 31.73 ± 7.64 | 20.40 ± 4.03 | 7.73 ± 2.13** |
| Serum Adipocytokines: | ||||||
| Adiponectin (μg/mL) | 17.44 ± 1.92 | 19.01 ± 2.01 | 42.59 ± 15.64** | 17.68 ± 1.68 | 16.25 ± 1.24 | 94.93 ± 16.94*** |
| Resistin (ng/mL) | 32.27 ± 2.88 | 37.11 ± 3.24 | 34.8 ± 5.55 | 61.85 ± 12.05 | 51.227 ± 13.83 | 23.99 ± 6.78* |
All data have been represented as Mean ± SEM.
p value obtained by using student t-test (paired) for parametric and Wilcoxon signed rank test for non-parametric variables at each time point when compared with baseline (p value <0.05*, <0.01**, <0.001***).