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. 2021 Dec 21;43:101233. doi: 10.1016/j.eclinm.2021.101233

Table 6.

Pooled prevalence and subgroup analyses of PTS.

Outcome measure Study (N) Sample (N) Prevalence(95%CI) I2%
PTS≤1 month 19 1,800 39.9 (30.8, 48.9) 94.5
Study setting
High-income countries 17 1,533 38.6 (30.0, 47.3) 92.7
Middle-income countries 2 267 46.3 (41.4, 51.3) NA
Study design
Cohort 15 1,354 35.3 (27.6, 42.9) 89.6
Cross-sectional 4 446 55.0 (33.3, 76.8) 96.1
Sample bias - representativeness
Representative 6 900 41.1 (26.8, 55.5) 94.4
Non-representative 13 900 39.3 (27.1, 51.6) 95.4
PTS symptoms assessment *a
Clinical interviews 1 158 24.1 (17.6, 31.5) NA
Self-reported 17 1,613 40.0 (30.8, 49.2) 93.9
Parents
Mothers 18 1,430 41.7 (32.0, 51.4) 93.9
Fathers 7 370 36.0 (14.0, 58.0) 96.6
Prematurity
Gestational age (GA)>33 weeks 12 1,037 42.2 (28.0, 56.5) 96.5
GA ≤33 7 763 35.8 (30.0, 41.6) 61.3
Measuring scales a
PPQ 6 600 39.4 (30.1, 48.6) 81.4
Other scales 12 1,171 38.9 (26.2, 51.5) 95.7
> 1 month ≤ 1 years 15 1,067 24.5 (17.4, 31.6) 90.7%
Study setting
High-income countries 13 915 24.3 (16.5, 32.2) 91.5
Middle-income countries 2 152 21.4 (15.1, 27.8) NR
Study design
Cohort study design 9 433 22.1 (13.6, 30.6) 87.3
Cross-sectional study design 6 634 27.6 (14.2, 40.9) 94.2
Selection bias- representativeness*
Representative 3 227 11.2 (6.5, 15.9) NR
Non-representative 12 840 27.3 (19.0, 35.7) 91.0
PTS symptoms assessment* a
Clinical interviews 1 189 11.1 (7.0, 16.5) NA
Self-reported 13 851 25.1 (17.2, 33.1) 90.8
Parents b
Mothers 13 830 25.7 (17.6, 33.8) 88.7
Fathers 5 237 28.5 (9.6,47.4) 93.2
Scales a
PPQ 2 185 24.9 (18.9, 31.1) NR
Other scales 12 855 23.9 (15.7, 32.2) 92.4%
PTS > 1 year 10 762 27.1 (20.7, 33.6) 75.6%
Study setting*
High-income countries 9 677 24.5 (19.5, 29.6) 55.5%
Middle-income countries 1 85 48.2 (37.3, 59.3) NA
Study design
Cohort study design 5 370 25.8 (19.2, 32.4) 46.8
Cross-sectional study design 5 392 27.5 (15.9, 39.0) 85.6
Sample representativeness
Non-representative
10
PTS symptoms assessment
Self-reported 10
Parents*
Mothers 10 661 27.6 (21.4, 33.9) 69.2
Fathers 2 101 16.1 (9.0, 23.2) NR
Prematurityc
GA >33 weeks 3 240 25.68(16.7, 35.0) 45.6
GA ≤33 weeks 6 455 30.5 (20.8, 40.3) 80.2
Measuring scalesa
PPQ 4 314 31.3 (26.2, 36.4) 0.0
Other scales 5 419 24.3 (13.4, 35.2) 85.6

Abbreviations: a Misund not included; b Schecter 2020 and Malin not included as parents data reported combined; c Clark not included as GA NR;* P <0.05 significant difference between subgroups; NR: Not reported as a few studies were pooled; NR: Not reported; PPQ: Perinatal Posttraumatic Stress Disorder Questionnaires.