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. 2021 Oct 31;37(Suppl 2):ii33–ii44. doi: 10.1093/ndt/gfab223

Table 1.

Uraemic toxins that might influence brain function

Small water-soluble compounds Protein-bound compounds Middle molecules

ADMA

SDMA

TMAO

Uric acid

Urea

Methylguanidine guanidine

Indoles

  • IS

  • Indoxyl glucuronide

  • IAA

  • Kynurenine

Cresols

  • pCS

  • p-cresyl glucuronide

Hippurates

  • HA

  • CMPF

B2M

IL-6

PTH

ADMA, asymmetric dimethylarginine; SDMA, symmetric dimethylarginine; TMAO, trimethylamine N-oxide; CMPF, 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid.