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. 2021 Dec 8;64(24):17936–17949. doi: 10.1021/acs.jmedchem.1c01264

Figure 2.

Figure 2

Short list of six compounds and 1 including their respective biochemical TNKS2 and cellular (HEK293) WNT/β-catenin signaling reporter assays IC50 values in nM. clog P and tPSA (in Å2) as calculated by DataWarrior v5.5.0. Moieties in color were different from 1.