Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Dec 27;219(2):e20211220. doi: 10.1084/jem.20211220

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Fay et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure S1. — Overview of cohousing setups throughout paper, with expanded pet store genotyping, weight loss, and pathogen discovery data. (A) Models of each cage setup (labeled A–F) used in analyses. Key on the right denotes analyses performed on each cage. See Table S1 for details on which cohousing designs were used for each figure in the manuscript. Cohousing setup F was used only for characterizing pet store mouse serology and assembling the Reepicheep virus genome. (B) Data from miniMUGA genotyping array (Sigmon et al., 2020) that determined the number of segregating markers between 3,653 pairs of inbred strains presented as a frequency distribution (minimum segregating markers = 6, maximum = 3,351, median = 2,654, mean = 2,445). In the 18 pet store mice, the number of segregating markers was 4,431 (black arrow), greatly exceeding these pairwise comparisons of diversity. (C) Maximum weight loss after cohousing. (D) Heatmap of virus reads as quantified using CCMetagen. (E) Specific amplification and identification of arenavirus RNA in pet store (top) and cohoused (bottom) mice. Data combined from D, n = 12 cages. ABX, antibiotics; LCMV, lymphocytic choriomeningitis virus.