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. 2021 Dec 27;219(2):e20211483. doi: 10.1084/jem.20211483

Figure S4.

Figure S4.

Splenic pDCs fail to exit the cell cycle and repress Myc in Irf8−/− mice. (A and B) Expression microarray analysis of pDCs (B220+SiglecH+) sorted from the spleens of Irf8+/+ and Irf8−/− mice (n = 3). (A) Average signal intensity of transcription factor probe sets for the indicated genotypes, with select probe sets annotated with corresponding gene symbols. (B) Heat map of differentially expressed genes (minimum twofold differential expression) grouped by gene ontology biological process annotations, as indicated. (C) Flow cytometry analysis of Ki-67 intracellular staining of splenic pDCs from Irf8+/+ and Irf8−/− mice (n = 5, two independent experiments).