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. Author manuscript; available in PMC: 2021 Dec 28.
Published in final edited form as: Sci Signal. 2018 Aug 28;11(545):eaar2125. doi: 10.1126/scisignal.aar2125

Fig. 5. BMPR1α alters Th1/Th17 gene expression.

Fig. 5.

(A) Principal component analysis of genes expressed by activated BMPR1α-sufficient and -deficient CD4+ T cells. Analysis included gene expression data from three samples of BMPR1α-sufficient and -deficient cells. (B) Genes differentially expressed in activated CD4+ T cells from WT and BMPR1αT− mice. Analysis included genes differentially expressed between three samples of BMPR1α-sufficient and - deficient cells. Colors show log2 fold change of the expression difference. (C) Metascape GO analysis of genes differentially expressed by activated WT and activated BMPR1α-deficient CD4+ T cells. (D) Transcript levels, fold change expression and p-values of genes differentially expressed in activated CD4+ T cells from WT and BMPR1αT− mice, related to inflammatory, immune and metabolic responses. Vertical bars represent average values of gene expression levels (fpkm) ± SD. All data are representative of three biological replicates.