Table 1.
Overview of the endoscopic ultrasound-guided celiac plexus neurolysis characteristics
Procedure
|
Chemical ablation of the celiac plexus
|
Indications | Chronic abdominal pain caused by: Pancreatic cancer; Chronic pancreatitis; Gallbladder carcinoma1 |
Contraindications[57] | Coagulation disorders; INR > 1.5; Platelet count < 50000/µL; Retroperitoneal abscess; Disturbed anatomy (difficulties in visualizing the celiac trunk and ganglia); Malformations of the celiac or superior mesenteric artery |
Serious complications (observed in 0.2% of the patients[63]) | Paraplegia; Retroperitoneal abscess; Ischemia with visceral injury |
Supporting evidence | Kaufman et al[50]; Wiersema et al[51]; Puli et al[54]; Wyse et al[55]; Arcidiacono et al[58] |
Only pivotal studies were so far conducted. INR: International normalized ratio.