Table-1:
Clinicopathologic features of patients and samples included in the assay development and validation in the research molecular diagnostic laboratory
| Characteristics | n | |
|---|---|---|
| Age | <50 years | 39 |
| >50 years | 136 | |
| Gender | Male | 95 |
| Female | 80 | |
| Tumor location | Right colon | 75 |
| Left and sigmoid colon | 92 | |
| Rectum | 5 | |
| Multiple primary tumors | 3 | |
| pT stage | pT1 | 0 |
| pT2 | 16 | |
| pT3 | 133 | |
| pT4 | 18 | |
| pT4a | 3 | |
| pT4b | 1 | |
| pN stage | pN0 | 76 |
| pN1 | 55 | |
| pN1a | 2 | |
| pN1b | 5 | |
| pN1c | 0 | |
| pN2 | 27 | |
| pN2a | 4 | |
| pN2b | 2 | |
| pN3 | 0 | |
| pNX | 4 | |
| pM stage | pM0 | 165 |
| pM1 | 5 | |
| pMX | 5 | |
| Grade | Low (well or moderately differentiated) | 145 |
| High (poorly differentiated) | 30 | |
| Time between date of surgery and gene expression analysis | < 5years | 20 |
| 5-10 years | 95 | |
| >10 years | 60 | |
| Samples | Matched flash frozen and formalin fixed paraffin embedded | 149 |
| Only formalin fixed paraffin embedded | 12 | |
| Only flash frozen | 4 | |