TABLE 3.
Hospital Outcomes by Neurological Manifestation Status and Acute SARS-CoV-2 or MIS-C Clinical Diagnosis
| Variables | Overall N = 1493 |
Neurological Manifestation N = 652 (44%) |
No Neurological Manifestation N = 841 (56%) |
P Value | Acute SARS-CoV-2 N = 1278 (86%) |
MIS-C N = 215 (14%) |
P Value |
|---|---|---|---|---|---|---|---|
| Highest level of care | |||||||
| Ward | 975 (65.3) | 319 (48.9) | 656 (78.0) | <0.001 | 909 (71.1) | 66 (30.7) | <0.001 |
| ICU | 518 (34.7) | 333 (51.1) | 185 (22.0) | 369 (28.9) | 149 (69.3) | ||
| Initial Glasgow Coma Scale score | n = 990 | n = 421 | n = 569 | n = 785 | n = 205 | ||
| 13-15 | 928 (93.7) | 369 (87.7) | 559 (98.3) | <0.001 | 735 (93.6) | 193 (94.1) | 0.094 |
| 9-12 | 40 (4.0) | 32 (7.6) | 8 (1.4) | 30 (3.8) | 10 (4.9) | ||
| 3-8 | 22 (2.2) | 20 (4.8) | 2 (0.4) | 20 (2.6) | 2 (1.0) | ||
| Initial PELOD (if ICU) | n = 229 | n = 149 | n = 80 | n = 118 | n = 111 | ||
| Median | 5 (1-11) | 6 (2-11) | 2 (1-10) | 0.086 | 3 (1-11) | 5 (2-11) | 0.032 |
| Hospital length of stay, days | 4.00 (2-7) | 5.00 (2-9) | 3.00 (2-6) | <0.001 | 3.00 (2-7) | 7.00 (5-9) | 0.008 |
| ICU length of stay, days | 4.00 (3-7) | 5.00 (3-8) | 3·00 (2-5.3) | <0.001 | 4.00 (2-7) | 4.00 (3-6) | 0.046 |
| Hospital mortality | 15 (1.0) | 14 (2·2) | 1 (0.1) | <0.001 | 11 (0.9) | 4 (1.9) | 0.174 |
| Hospital disposition | n = 1462 | n = 633 | n = 829 | n = 1247 | n = 215 | ||
| Home | 1391 (95.2) | 680 (91·6) | 811 (97.8) | <0.001 | 1186 (95.1) | 205 (95.3) | 0.730 |
| Inpatient rehabilitation | 25 (1.7) | 22 (3·5) | 3 (0.4) | 20 (1.6) | 5 (2.3) | ||
| Long-term care facility | 2 (0.1) | 2 (0·3) | 0 (0.0) | 2 (0.2) | 0 (0.0) | ||
| Other | 44 (3.0) | 29 (4·6) | 15 (1.8) | 39 (3.1) | 5 (2.3) |
Abbreviations:
ICU = Intensive care unit
IQR = Interquartile range
MIS-C = Multisystem inflammatory syndrome in children
PELOD = Pediatric Logistic Organ Dysfunction
SARS-CoV-2 = Severe acute respiratory syndrome coronavirus 2
Results are reported as median (IQR) versus n (%).