TABLE 4.

Multivariable Logistic Regression for the Association of Patient Characteristics With Occurrence of Any Neurological Manifestation (Overall Cohort)

Variable	Odds Ratio	95% Confidence Interval	P Value
Age	1.10	1.07, 1.13	<0.001
Female sex	1.16	0.04, 29.84	0.917
Race
Asian	0.48	0.05, 3.41	0.466
Black	0.30	0.04, 1.95	0.210
Native American or Pacific Islander	0.30	0.01, 6.85	0.465
White	0.45	0.05, 2.87	0.397
American Indian or Alaskan Native	1.00	-	-
Other	0.39	0.05, 2.60	0.336
Hispanic ethnicity	0.88	0.61, 1.27	0.499
MIS-C versus acute SARS-CoV-2	2.16	1.45, 3.24	<0.001
Pre-existing condition
Neurological	3.48	2.37, 5.15	<0.001
Cardiovascular	0.61	0.37, 0.99	0.051
Respiratory	0.88	0.61, 1.29	0.514
Renal or urologic	0.64	0.34, 1.17	0.153
Gastrointestinal	0.68	0.44, 1.07	0.095
Hematologic or immunologic	0.74	0.47, 1.17	0.206
Metabolic	1.65	1.04, 2.66	0.036
Congenital or genetic defect	1.09	0.68, 1.76	0.709
Malignancy	1.03	0.57, 1.88	0.917
Premature or neonatal	1.27	0.78, 2.03	0.332
Technology dependence	0.81	0.44, 1.47	0.497
Transplantation	1.18	0.51, 2.71	0.695
Other, nonneurological	1.08	0.70, 1.66	0.729
Constitutional symptoms
Fever	1.30	0.68, 1.24	0.093
Cough	0.92	0.68, 1.24	0.607
Anorexia	1.28	0.94, 1.74	0.116
Diarrhea	0.99	0.70, 1.39	0.949
Throat pain	1.74	1.16, 2.64	0.008
Abdominal pain	1.43	1.03, 2.00	0.035
Obesity	1.13	0.73, 1.75	0.575

Abbreviations:

MIS-C = Multisystem inflammatory syndrome in children

SARS-CoV-2 = Severe acute respiratory syndrome coronavirus 2