TABLE 6.
Multivariable Logistic Regression for the Association of Patient Characteristics With Occurrence of Any Neurological Manifestation (MIS-C Subcohort)
| Variable | Odds Ratio | 95% Confidence Interval | P Value |
|---|---|---|---|
| Age | 1.16 | 1.06, 1.27 | 0.001 |
| Female sex | 1.46 | 0.66, 3.27 | 0.353 |
| Race∗ | |||
| Asian | 1.70 | 0.23, 15.83 | 0.612 |
| Black | 0.88 | 0.33, 2.27 | 0.791 |
| White | Reference | - | - |
| Other | 0.31 | 0.16, 1.76 | 0.305 |
| Hispanic ethnicity | 0.45 | 0.14, 1.38 | 0.164 |
| Pre-existing condition | |||
| Neurological | 3.84 | 0.76, 23.91 | 0.121 |
| Cardiovascular | 1.80 | 0.33, 13.31 | 0.525 |
| Respiratory | 4.98 | 1.21, 27.88 | 0.040 |
| Gastrointestinal | 0.03 | 0.001, 0.27 | 0.005 |
| Metabolic | 1.41 | 0.33, 14.78 | 0.678 |
| Other, nonneurological† | 0.63 | 0.20, 2.13 | 0.436 |
| Constitutional symptoms | |||
| Fever | 0.37 | 0.02, 3.31 | 0.416 |
| Cough | 0.98 | 0.43, 2.25 | 0.954 |
| Anorexia | 0.71 | 0.32, 1.55 | 0.391 |
| Diarrhea | 0.86 | 0.38, 1.93 | 0.717 |
| Throat pain | 2.19 | 0.86, 5.97 | 0.110 |
| Abdominal pain | 5.36 | 2.39, 12.63 | <0.001 |
| Obesity | 1.45 | 0.34, 7.94 | 0.641 |
Abbreviations:
MIS-C = Multisystem inflammatory syndrome in children
SARS-CoV-2 = Severe acute respiratory syndrome coronavirus 2
∗
American Indian or Alaskan Native and Native American or Pacific Islander collapsed into other race due to small sample size.
†
Pre-existing Renal, Congenital or Genetic, Defect Malignancy, Premature or Neonatal, Technology dependence, and Transplantation conditions were grouped into the Other, nonneurological group due to small sample size.