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. Author manuscript; available in PMC: 2021 Dec 28.
Published in final edited form as: Sci Transl Med. 2021 Jan 13;13(576):eabc6245. doi: 10.1126/scitranslmed.abc6245

Fig. 4. PK for P4/TSA treatment.

Fig. 4.

P4 (left axis) and TSA (right axis) concentrations in (A) plasma, (B) cervical tissue, (C) proximal myometrial tissue, and (D) distal myometrial tissue collected from healthy dams after a single vaginal P4/TSA NS dose on E15. An empty square symbol indicates that TSA concentrations in all samples were below the lower limit of quantification (0.2 ng/ml or ng/g) at that time point. Gray dashed lines represent mean endogenous concentrations of P4 from untreated healthy E15 dams. Data are presented as median ± interquartile range (n = 3).