Table 1. Characteristics of patients, GBM specimens, and corresponding neurospheres.
BT, brain tumor; MES, mesenchymal; PN, proneural; CLAS, classical; ND, not determined; Unmet, unmethylated; Met, methylated; OS, overall survival; F, female; M, male.
| GBM | CSPG4 expression | % CSPG4 GBM-NS | OS | Subtype | MGMT methylation | Age | Gender | |
|---|---|---|---|---|---|---|---|---|
| Specimens | Vessels | |||||||
| BT168 | +++ | ++ | 49.0 | 6.0 | MES | Unmet | 78 | F |
| BT205 | + | + | 85.0 | 2.0 | PN | Unmet | 73 | M |
| BT423 | ++ | ++ | 98.7 | 6.5 | CLAS | Met | 43 | F |
| BT273 | + | +/− | 85.9 | 14.0 | CLAS | Met | 59 | M |
| BT275 | + | ++ | 97.4 | 15.0 | CLAS | Met | 67 | F |
| BT299 | ++ | + | 99.0 | 6.5 | PN | Unmet | 50 | M |
| BT308 | + | ++ | 96.0 | 3.0 | PN | Unmet | 76 | M |
| BT326 | + | ++ | 63.0 | 6.5 | PN | Unmet | 28 | M |
| BT328 | + | +/− | 83.2 | 6.0 | MES | Unmet | 56 | M |
| BT358 | ++ | ++ | 95.6 | 22.0 | MES | Unmet | 64 | F |
| BT373 | ++ | ++ | 55.4 | 3.0 | PN | Unmet | 65 | M |
| BT417 | + | ++ | 90.0 | 11.0 | CLAS | Met | 53 | M |
| BT462 | + | ++ | 42.5 | 10.0 | CLAS | Unmet | 71 | M |
| BT482 | ++ | + | 82.6 | 8.0 | MES | Unmet | 38 | M |
| BT517 | ++ | ++ | 91.9 | 8.0 | CLAS | Unmet | 48 | M |
| BT137 | + | ++ | 6.0 | PN | Unmet | 37 | F | |
| BT140 | + | ++ | 10.0 | MES | Unmet | 47 | F | |
| BT150 | + | ++ | 10.0 | CLAS | Unmet | 61 | M | |
| BT157 | + | +/− | 9.0 | MES | Unmet | 54 | M | |
| BT202 | + | ++ | 4.0 | MES | Unmet | 70 | M | |
| BT206 | + | ++ | 4.5 | CLAS | Unmet | 69 | M | |
| BT211 | + | ++ | 4.5 | MES | ND | 61 | M | |
| BT209 | + | ++ | 4.5 | PN | Unmet | 56 | M | |
| BT219 | + | + | 5.0 | MES | Unmet | 55 | M | |
| BT235 | ++ | ++ | 24.5 | CLAS | Met | 70 | M | |
| BT261 | ++ | ++ | 3.0 | CLAS | Unmet | 65 | M | |
| BT334 | ++ | ++ | 9.0 | CLAS | Unmet | 63 | M | |
| BT513 | ++ | + | 13.0 | MES | Unmet | 58 | M | |
| BT241 | + | ++ | 13.0 | ND | Unmet | 70 | M | |
| BT248 | + | ++ | 6.0 | ND | Met | 64 | M | |
| BT347 | ++ | ++ | 29.0 | ND | Met | 57 | F | |
| BT302 | +/− | ++ | 16.0 | 60.0 | MES | Unmet | 19 | F |
| BT337 | +/− | ++ | 69.0 | 17.5 | PN | Met | 65 | M |
| BT379 | +/− | ++ | 97.0 | 16.0 | CLAS | Unmet | 73 | M |
| BT422 | +/− | +/− | 59.1 | 36.0 | CLAS | Unmet | 70 | M |
| BT480 | +/− | ++ | 59.0 | 13.0 | MES | Unmet | 69 | F |
| BT483 | +/− | ++ | 97.7 | 15.0 | PN | Met | 54 | M |
| BT487 | +/− | ++ | 70.6 | 24.0 | MES | Unmet | 72 | M |
| BT500 | +/− | ++ | 84.0 | 9.5 | CLAS | Unmet | 67 | F |
| BT155 | +/− | ++ | 13.0 | CLAS | Unmet | 46 | F | |
| BT245 | +/− | ++ | 46.0 | PN | Met | 57 | F | |
| BT274 | − | + | 18.0 | PN | Unmet | 50 | M | |
| BT279 | +/− | + | 15.0 | CLAS | Unmet | 60 | F | |
| BT283 | +/− | + | 9.5 | CLAS | Met | 46 | F | |
| BT490 | +/− | ++ | 16.0 | PN | Unmet | 76 | F | |
| BT175 | +/− | + | 12.5 | ND | Unmet | 63 | M | |