FIGURE 6.

Examples of 3D reconstructed microglia in cortical gray matter in control brain (A) and SCZ brain (E). Microglia morphology indicated less ramification by having a shorter process lengths and smaller numbers of processes in cortical gray matter (B, C) in SCZ group compared with controls. Branching pattern alterations of microglia in cortical gray matter indicated the number of branching intersections was significantly lower in SCZ cases versus the control group (D) at various distances away from the cell soma. Age‐association testing demonstrated a significant negative correlation between ramification of microglia and age of SCZ cases (F, G), **p < 0.01, ***p < 0.001