TABLE 1.
Summary of the clinical information of the human postmortem cases
| Group | Age (years) | Sex | PMI (h) | Ethnicity | Neurolopathological findings | Nicotine use | Cause of death | Manner of death | Approximate (years) diagnosed with SCZ | Neuroleptics |
|---|---|---|---|---|---|---|---|---|---|---|
| SCZ1 | 48 | F | 48.00 | Caucasian | Normal brain | N | Myocardial infarction | Natural | 30 | Unknown |
| SCZ2 | 55 | F | 20.75 | Caucasian | Normal brain | H | Blunt force trauma | suicide | 35 | Unknown |
| SCZ3 | 49 | M | 21.00 | Caucasian | focal meningitis | U | Bronchopneumonia | Natural | 25 | Unknown |
| SCZ4 | 40 | M | 19.00 | Caucasian | Normal brain | H | Cardiopulmonary arrest | Natural | 23 | Unknown |
| SCZ5 | 53 | F | 17.00 | Caucasian | Mild anoxic ischemic changes | H | Food asphyxiation | Accidental | 30 | Unknown |
| SCZ6 | 62 | F | 54.72 | African American | Normal brain | H | Cardiopulmonary arrest | Natural | 42 | Haloperidol |
| SCZ7 | 34 | F | 25.00 | Caucasian | Normal brain | L | Accidental | Accidental | 16 | Unknown |
| SCZ8 | 30 | F | 24.10 | African American | Normal brain | M | Gunshot | Suicide | 12 | Unknown |
| SCZ9 | 36 | M | 24.00 | Caucasian | Normal brain | M | Hanging | Suicide | 22 | Olanzapine |
| SCZ10 | 62 | M | 11.41 | Caucasian | Normal brain | M | Acute coronary insufficiency | Natural | 40 | Clozapine |
| SCZ11 | 55 | M | 13.00 | Caucasian | Normal brain | M | Sepsis because of pneumonia | Natural | 40 | Fluphenazine |
| SCZ12 | 56 | M | 19.00 | Caucasian | Normal brain | N | Arteriosclerotic heart disease | Natural | 36 | Chlorpromazine |
| SCZ13 | 42 | M | 17.00 | Caucasian | Normal brain | H | Cardiomegaly | Natural | 32 | Quetiapine |
| SCZ14 | 39 | M | 18.00 | Caucasian | Normal brain | M | Arteriosclerotic heart disease | Natural | 20 | Quetiapine |
| SCZ15 | 59 | M | 24.00 | Caucasian | Normal brain | H | Hanging | Suicide | 40 | Haloperidol |
| SCZ16 | 46 | M | 46.00 | Caucasian | Normal brain | N | Cardiopulmonary arrest | Natural | 28 | Haloperidol |
| Mean | 48 | 25.12 | 29.44 | |||||||
| C1 | 63 | M | 20.50 | Caucasian | Normal brain | H | Cardiac arrest | Natural | ||
| C2 | 63 | F | 17.70 | Caucasian | Normal brain | M | Coronary artery disease | Natural | ||
| C3 | 54 | F | 17.51 | Caucasian | Normal brain | N | Motor vehicle accident | Accidental | ||
| C4 | 34 | M | 28.35 | Caucasian | Normal brain | N | Drowning | Accidental | ||
| C5 | 60 | M | 25.88 | Caucasian | Normal brain | L | Electrocution | Accidental | ||
| C6 | 51 | F | 15.00 | Caucasian | Normal brain | M | Pneumonia, cirrhosis | Natural | ||
| C7 | 36 | M | 20.30 | Caucasian | Normal brain | M | Undetermined causes | Unknown | ||
| C8 | 46 | M | 17.75 | Caucasian | Normal brain | L | Gunshot | Accidental | ||
| C9 | 47 | F | 20.00 | Caucasian | Normal brain | H | Arteriosclerotic heart disease | Natural | ||
| C10 | 50 | M | 20.73 | Caucasian | Normal brain | M | Acute myocardial infarction | Natural | ||
| C11 | 66 | M | 23.28 | Caucasian | Normal brain | M | Cardiopulmonary arrest | Natural | ||
| C12 | 63 | M | 12.00 | Caucasian | Normal brain | M | Coronary artery disease | Natural | ||
| C13 | 63 | M | 16.91 | Caucasian | Normal brain | N | Arteriosclerotic heart disease | Natural | ||
| Mean | 54 | 19.69 |
Abbreviations: C, controls; F, female; H, heavy smoker casual or ≥20 cigarettes/day; h, hours; L, light smoker casual or <1 cigarette/day; M, male; M, moderate smoker ≤19 cigarettes/day; N, nonsmoker; PMI, postmortem interval; SCZ, Schizophenia; U, unknown.