TABLE 5.

Summary of microglia changes by region

Region—Tissue type	Microglia density	Microglia nearest neighbor distances	Microglia clustering	Microglia morphology changes
				Soma size	Overall branching	Extension lengths
BA9—Cortical gray matter	↑	↓	nc	↑	↓	↓
BA22—Cortical gray matter	↑	nc	nc	↑	↓	↓
BA32—Cortical gray matter	↑	↓	nc	nc	↓	nc
BA9—SCWM	↑	↓	nc	↑	↓	nc
BA22—SCWM	↑	↓	nc	↑	↓	nc
BA32—SCWM	nc	nc	nc	↑	↓	↓
BA32—CC	nc	↓	nc	nc	nc	nc

Arrows indicating the increase (up arrow) and decrease (down arrow) of microglia cell densities, distances to the nearest neighbor, clustering pattern, and morphology. nc = no changes in the measurement between schizophrenia (SCZ) and control in the cortical gray matter, subcortical white matter (SCWM), and corpus callosum (CC) regions.