Table 1.
Baseline patients characteristics (n = 145)
| HBV (38) | HCV (60) | NAFLD (47) | P value | |
|---|---|---|---|---|
| Males n, % | 29 (76) | 40 (67) | 19 (40) | 0.0016 |
| Women n, % | 9 (24) | 20 (33) | 28 (60) | |
| Mean age at HCC dx ± SD | 62 ± 11 | 67 ± 10 | 64 ± 7 | 0.0030 |
| Type 2 diabetes, n (%) | 8 (21) | 17 (29) | 35 (74) | < 0.0001 |
| Decompensation, n (%) | ||||
| HE | 1 (3) | 3 (5) | 11 (23) | 0.0017 |
| Ascites/volume overload | 0 (0) | 2 (6) | 19 (34) | < 0.0001 |
| Child-Pugh score | ||||
| A | 36 (95) | 51 (85) | 23 (52) | < 0.001 |
| B | 2 (5) | 8 (13) | 18 (41) | |
| C | 0 (0) | 1 (2) | 3 (7) | |
| Median INR (IQR) | 1.1 (1.0–1.2) | 1.1 (1.1–1.2) | 1.2 (1.1–1.3) | 0.0530 |
| Median AST (IQR) | 50 (25–52) | 85 (44–114) | 49 (35–60) | < 0.0001 |
| Median ALT (IQR) | 39 (26–59) | 58 (35–107) | 32 (23–39) | < 0.0001 |
| Median albumin (IQR) | 4.2 (3.9–4.7) | 3.8 (3.4–4.2) | 3.6 (3.2–4.0) | < 0.0001 |
| Median total bilirubin (IQR) | 0.8 (0.5–0.9) | 1.1 (0.8–1.6) | 1.3 (0.8–2.3) | 0.0010 |
| Median platelets (IQR) | 170 (95–195) | 115 (77–186) | 94 (65–146) | 0.0010 |
| Screened for HCC, n (%) | 28 (74) | 49 (82) | 28 (60) | 0.0391 |
| Family history HCC, n (%) | 14 (39) | 1 (2) | 2 (4) | < 0.0001 |
| Family history LD, (%) | 4 (29) | 6 (11) | 16 (34) | 0.0130 |
HCC: Hepatocellular carcinoma; INR: international normalized ratio; AST: aspartate aminotransferase; ALT: alanine aminotransferase; LD: liver disease.