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. 2021 Dec 8;37(10):565–574. doi: 10.1089/jop.2021.0068

Table 2.

Blood Pressure, Intraocular Pressure, and Ocular Perfusion Pressure at Baseline, with 1-Week Timolol Treatment, and with 1-Week Latanoprost Treatment in n = 121 Nonglaucomatous Volunteers

 
Baseline
Timolol
Latanoprost
Measure Mean (SD); units: mmHg
SBP 124.4 (14.7) 120.8 (13.7)a 123.1(13.0)
DBP 77.1 (10.3) 75.9 (10.5) 77.6 (9.7)
IOP 15.8 (3.0) 13.8 (2.5)a 13.0 (2.1)a
MOPP 46.8 (8.1) 48.5 (7.9)a 49.6 (8.2)a
SOPP 108.5 (14.4) 106.9 (13.7)a 110.2 (13.1)a
DOPP 61.3 (10.8) 62.0 (10.8)a 64.7 (10.0)a

MOPP = ⅔ [DBP + ⅓ (SBP − DBP)] − IOP. SOPP: (SBP − IOP). DOPP: (DBP − IOP).

a

Statistically significant difference (P < 0.05) from baseline in linear mixed-effect models.

DBP, diastolic blood pressure; DOPP, diastolic ocular perfusion pressure; IOP, intraocular pressure; MOPP, mean ocular perfusion pressure; SBP, systolic blood pressure; SOPP, systolic ocular perfusion pressure.