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Identification of a simple gene classifier. (A) Heatmap of the expression level of the PIE classifier (PIE classifier: prognosis and ICB therapeutic efficacy of the ccRCC classifier). Concordance of molecular clusters prediction in TCGA (B), E-MTAB-1980 (C) Check-mate 025 (D) cohorts between the PIE classifier and molecular classification based on CNMF algorithm.
