Table 1.
Clinicopathological characteristics of ccRCC patients in the TCGA cohort.
| Characteristics | All Patients | Cluster1 | Cluster2 | p-value |
|---|---|---|---|---|
| Patients, no. (%) | 509 (100) | 176 (34.6) | 333 (65.4) | |
| T stage, no. (%) | <0.001 | |||
| T1 | 261 (51.3) | 58 (33.0) | 203 (61.0) | |
| T2 | 68 (13.3) | 23 (13.1) | 45 (13.5) | |
| T3 | 170 (33.4) | 87 (49.4) | 83 (24.9) | |
| T4 | 10 (2.0) | 8 (4.5) | 2 (0.6) | |
| N status, no. (%) | 0.005 | |||
| N0 | 227 (44.6) | 78 (44.3) | 149 (44.7) | |
| N1 | 15 (2.9) | 11 (6.3) | 4 (1.2) | |
| Unknown | 267 (52.5) | 87 (49.4) | 180 (54.1) | |
| M stage, no. (%) | <0.001 | |||
| M0 | 406 (79.8) | 125 (71.0) | 281 (84.4) | |
| M1 | 76 (14.9) | 46 (26.1) | 30 (9.0) | |
| Unknown | 27 (5.3) | 5 (2.9) | 22 (6.6) | |
| Stage, no. (%) | <0.001 | |||
| Stage I | 255 (50.1) | 54 (30.7) | 201 (60.4) | |
| Stage II | 56 (11.0) | 19 (10.8) | 37 (11.1) | |
| Stage III | 115 (22.6) | 54 (30.7) | 61 (18.3) | |
| Stage IV | 83 (16.3) | 49 (27.8) | 34 (10.2) | |
| Grade, no. (%) | <0.001 | |||
| 1 | 12 (2.4) | 1 (0.6) | 11 (3.3) | |
| 2 | 217 (42.6) | 45 (25.6) | 172 (51.7) | |
| 3 | 200 (39.3) | 72 (40.9) | 128 (38.4) | |
| 4 | 72 (14.1) | 56 (31.8) | 16 (4.8) | |
| Unknown | 8 (1.6) | 2 (1.1) | 6 (1.8) | |
| Survival status, no. (%) | <0.001 | |||
| Alive | 343 (67.4) | 83 (47.2) | 260 (78.1) | |
| Dead | 166 (32.6) | 93 (52.8) | 73 (21.9) | |
| Survival time | <0.001 | |||
| Median months (range) | 45.8 (1-149.0) | 38.8 (1-133.6) | 49.5 (37.5-149.0) |