Table 2.
The IHI trigger tool medication module triggers and modifications for tools A and B
| IHI MMTT trigger | Tool A trigger | Tool B trigger |
|---|---|---|
| M1: C. difficile-positive stool | – | M1: C. difficile-positive stool a |
| M2: PTT >100 sec | M2: Thromboplastin time 1 >120 sec and thromboplastin time 2 >13 sec | M2: Thromboplastin time 1 >120 sec and thromboplastin time 2 >13 sec |
| M3: INR >6 | M3: INR > 4b | M3: INR > 4b |
| M4: Glucose <50 mg/dl | M4: Glucagon or 40% and 50% glucosec | M4: Glucagon or 40% and 50% glucosec |
| M5: Rising BUN or serum creatinine two times (2×) over baseline | M5: Rising urea or creatinine 2× above upper limit of normal | M5: Rising urea or creatinine 2× above upper limit of normal |
| M6: Vitamin K administration | M6: Vitamin K administration | M6: Vitamin K administration |
| M7: Diphenhydramine (benadryl) administration | M7: Antihistamine administration | M7: Antihistamine administration |
| M8: Romazicon (flumazenil) administration | M8: Flumazenil administration | M8: Flumazenil administration |
| M9: Naloxone (Narcan) administration | M9: Naloxone administration | M9: Naloxone administration |
| M10 Anti-emetic administration | – | – |
| M11 Oversedation/hypotension | M11.1: Hypotension (SBP <80 mmHg)c | M11.1: Hypotension (SBP <80 mmHg)c |
| M12 Abrupt medication stop | – | – |
| M13 Other | Rivaroxaban drug-level or anti-factor Xa activity | Rivaroxaban drug-level or anti-factor Xa activity |
Notes: aNon-digital trigger. bAs per German IHI MMTT Version. cAs per UK IHI MMTT Version.
Abbreviations: M, medication module triggers; SBP, systolic blood pressure.