Table 1.

Three Cases of IgA Vasculitis During Immune Checkpoint Inhibitor Therapy

	Our Case	Belkaid et al2	Casafont-Solé et al5
Age (years), sex	50, female	70, male	64, male
Disease	Renal cell carcinoma	Metastatic melanoma	Squamous cell carcinoma of the lung
ICI	Nivolumab	Nivolumab	Durvalumab
Treatment duration before IgA vasculitis	25 cycles (5 cycles after resumption)	4 cycles of nivolumab plus ipilimumab and 4 cycles of nivolumab monotherapy	5 cycles
Other irAEs	Liver dysfunction	No	Polymyalgia rheumatica
Other symptoms as IgA vasculitis except for skin	Myalgia	Abdominal pain, diarrhea, arthralgia, proteinuria, hematuria	Proteinuria, hematuria
Cessation of ICI	Temporary	Yes	Yes
Treatment	Oral PSL	Intravenous boluses of methylprednisolone, oral PSL	Oral PSL

Abbreviations: ICI, immune checkpoint inhibitor; irAEs, immune-related adverse events; PSL, prednisolone; PD-1, programmed cell death protein 1; CTLA-4, cytotoxic T-lymphocyte-associated antigen 4; PD-L1, programmed cell death ligand 1.