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. 2021 Dec 14;8:763692. doi: 10.3389/fnut.2021.763692

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Copyright © 2021 Wei, Fan, Jia, Zhang, Zhang, Zhang, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sea cucumber intestinal peptide inhibits the growth of tumor cells in zebrafish. The wild-type AB zebrafish do not produce red fluorescence. CM-Dil labeled cells injected into the yolk sac of zebrafish can produce red fluorescence at a certain wavelength. The total fluorescence intensity is positively correlated with the number of cancer cells. (A) Control group; (B) Model group; (C) Capecitabine group, administration of 20 μg/ml capecitabine by water-soluble; (D) Low concentration SCIP group, administration of 27.8 μg/ml SCIP by water-soluble; (E) Middle concentration SCIP group, administration of 83.3 μg/ml SCIP by water-soluble; (F) High concentration SCIP group, administration of 250 μg/ml SCIP by water-soluble. “*” means that the experimental group was significant. On the contrary, the “#” means that the experimental group is not significant.