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. Author manuscript; available in PMC: 2022 Jan 15.
Published in final edited form as: Neuroscience. 2020 Nov 24;453:206–221. doi: 10.1016/j.neuroscience.2020.11.029

Figure 2.

Figure 2.

Systemic application of SSRIs reduced PGES following seizures in amygdala kindled mice. (A,B) PGES duration and seizure duration (C,D) following seizures induced during wake and non-rapid eye movement (NREM) in mice pre-treated with citalopram (A,C; CIT; 20 mg/kg, i.p.) or fluoxetine (B,D; FLX; 10 mg/kg, i.p.). *, p < 0.05. (E-H) Representative spectral plots demonstrating PGES duration following amygdala stimulation in kindled mice that received (E,F) CIT or (G,H) FLX prior to seizures induced during wake (E,G) or NREM (F,H).Y-axis: event related spectral perturbation (ERSP) power in decibels (dB).