Table 2. Association of clinicopathological characteristics with GDI2 expression.

Characteristics with high- and low-GDI2 expression	Odds ratio (OR)	P value
T stage (T2&T3&T4 vs. T1)	1.45 (0.96-2.19)	0.076
N stage (N1 vs. N0)	2.60 (0.33-52.95)	0.411
M stage (M1 vs. M0)	0.94 (0.11-7.94)	0.952
Pathologic stage (Stage II&Stage III&Stage IV vs. Stage I)	1.40 (0.92-2.14)	0.119
Histologic grade (G3&G4 vs. G1&G2)	1.58 (1.03-2.44)	0.035*
Residual tumor (R1&R2 vs. R0)	1.36 (0.52-3.65)	0.525
Child-Pugh grade (B&C vs. A)	2.05 (0.84-5.31)	0.122
Fibrosis ishak score (1/2&3/4&5/6 vs. 0)	1.51 (0.86-2.69)	0.158
Adjacent hepatic tissue inflammation (Mild&Severe vs. None)	1.46 (0.87-2.45)	0.150
Vascular invasion (Yes vs. No)	1.18 (0.74-1.89)	0.475
Tumor status (With tumor vs. Tumor free)	1.25 (0.82-1.91)	0.303
TP53 status (Mut vs. WT)	1.51 (0.95-2.40)	0.083
Characteristics with GDI2 expression (TPM value)	Odds ratio (OR)	P value
T stage (T2&T3&T4 vs. T1)	1.01 (1.00-1.01)	<0.001**
N stage (N1 vs. N0)	1.01 (0.99-1.02)	0.309
M stage (M1 vs. M0)	1.00 (0.98-1.01)	0.755
Pathologic stage (Stage II&Stage III&Stage IV vs. Stage I)	1.01 (1.00-1.01)	0.001**
Histologic grade (G3&G4 vs. G1&G2)	1.01 (1.00-1.01)	0.007**
Residual tumor (R1&R2 vs. R0)	1.00 (1.00-1.01)	0.236
Child-Pugh grade (B&C vs. A)	1.01 (1.00-1.01)	0.130
Fibrosis ishak score (1/2&3/4&5/6 vs. 0)	1.00 (1.00-1.01)	0.112
Adjacent hepatic tissue inflammation (Mild&Severe vs. None)	1.01 (1.00-1.01)	0.051
Vascular invasion (Yes vs. No)	1.00 (1.00-1.01)	0.094
Tumor status (With tumor vs. Tumor free)	1.00 (1.00-1.01)	0.065
TP53 status (Mut vs. WT)	1.01 (1.00-1.01)	<0.001**

^*P < 0.05; ^** P < 0.01.