Figure 2.

Trichophyton indotineae susceptibility to terbinafine reported from 4 countries. A) Relationships between terbinafine MIC and codon changes reported in isolates from different countries. Grey line shows terbinafine susceptibility threshold of 0.2 μg/mL. Available MICs were determined using the Clinical Laboratory and Standards Institute (https://clsi.org) or EUCAST (https://eucast.org) methods. Data show mean values. B) Prevalence of substitution points in the gene encoding SQLE. Sources shown in the Appendix. SQLE, squalene epoxidase enzyme.